Title:
CYP17阻害剤としての1,3-二置換イミダゾリジン-2-オン誘導体
Document Type and Number:
Japanese Patent JP5456891
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof, where R53, R54, p, q, and n are as defined herein. The compounds of the present invention have been found to be useful as 17α-hydroxylase/C17,20-lyase inhibitors.
Inventors:
Mark Gee Bock
Christoph Gaul
Venkateshwar Rao Gunmadi
Saumitra Sengupta
Christoph Gaul
Venkateshwar Rao Gunmadi
Saumitra Sengupta
Application Number:
JP2012516752A
Publication Date:
April 02, 2014
Filing Date:
June 24, 2010
Export Citation:
Assignee:
Novartis Age
International Classes:
C07D401/04; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/498; A61K31/4985; A61K31/506; A61K31/5377; A61K45/00; A61P13/08; A61P29/00; A61P35/00; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D495/04
Domestic Patent References:
| JP8176111A | ||||
| JP7233162A | ||||
| JP52105182A | ||||
| JP49070968A | ||||
| JP2002302488A | ||||
| JP2005524620A | ||||
| JP2000511532A | ||||
| JP6256343A |
Foreign References:
| WO2008044700A1 | ||||
| WO2009097567A1 | ||||
| WO2009143039A1 | ||||
| WO2004009558A1 |
Other References:
Bioorg. Med. Chem. Lett.,2005年,15,4989-4993
Pesticide Biochemistry and Physiology,1995年,52,45-59
F. SACZEWSKI,2-CHLORO-4,5-DIHYDROIMIDAZOLE;I,REACTIONS WITH SOME HETEROAROMATIC 以下備考,SYNTHESIS,1984年 2月 1日,P170-172,N-OXIDES,CYCLIC NITRONES,AND ALDOXIMES
Pesticide Biochemistry and Physiology,1995年,52,45-59
F. SACZEWSKI,2-CHLORO-4,5-DIHYDROIMIDAZOLE;I,REACTIONS WITH SOME HETEROAROMATIC 以下備考,SYNTHESIS,1984年 2月 1日,P170-172,N-OXIDES,CYCLIC NITRONES,AND ALDOXIMES
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai