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Title:
15D-PGJ2 AND METHOD USING 15D-PGJ2
Document Type and Number:
Japanese Patent JP2006008583
Kind Code:
A
Abstract:

To clarify mechanism of a circadian rhythm and to provide a circadian rhythm and to provide a method for regulating the circadian rhythm and to provide an anticancer agent and to provide a means for detecting abnormality of the circadian rhythm, cancer onset risk and stress.

The present invention provides 15d-PGJ2 (15-deoxy-delta 12,14-prostaglandin J2) of per2 gene for promoting expression of per2 gene based on a new knowledge in which 15d-PGJ2 promotes expression of per2 gene and a method for promoting expression of per2 gene by using 15d-PGJ2. The present invention provides a circadian rhythm-regulating agent and anticancer agent each containing 15d-PGJ2 and a method for regulating the circadian rhythm by using 15d-PGJ2. The present invention further provides 15d-PGJ2 as a marker for detecting abnormality of the circadian rhythm, the cancer onset risk and the stress and a method for detecting abnormality of the circadian rhythm, the cancer onset risk and the stress by using 15d-PGJ2 as a marker.


Inventors:
YAMAMOTO TAKUO
NAKAHATA YASUKAZU
TAKUMI TORU
Application Number:
JP2004187372A
Publication Date:
January 12, 2006
Filing Date:
June 25, 2004
Export Citation:
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Assignee:
SONY CORP
International Classes:
C07C405/00; A61K31/5575; A61P25/20; A61P35/00; A61P43/00
Domestic Patent References:
JP2002500179A2002-01-08
JP2002536294A2002-10-29
JP2001220355A2001-08-14
JP2001510462A2001-07-31
JP2001507706A2001-06-12
Foreign References:
WO2001047555A12001-07-05
WO2000030628A22000-06-02
WO2000001820A22000-01-13
Attorney, Agent or Firm:
Kaoru Watanabe



 
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