Title:
【発明の名称】15-デヒドロキシ-16-オキソプロスタグランジン類
Document Type and Number:
Japanese Patent JP2511579
Kind Code:
B2
Abstract:
A compound of the formula: wherein L and M are hydrogen atom, hydroxy, lower alkyl, hydroxy(lower)alkyl or oxo, provided that at least one of L and M is not hydrogen atom and that the five-membered ring may have one or two double bonds, X1 and X2 are hydrogen atom, halogen atom or lower alkyl, Y is -CH2-CH2-, -CH=CH-, -C=C- or -CO-CH2-, Z is -CH2-CH2-CH2-, -CH=CH-CH2 or -CH2-CH=CH-, R is hydrogen atom, lower alkyl, lower cycloalkyl, monocyclic aryl, monocyclic aryl(lower)alkyl or monocyclic aroyl(lower)alkyl, R2 is single bond or lower alkylene, R3 is lower alkyl which is unsubstituted or substituted with halogen, lower cycloalkyl which is unsubstituted or substituted with lower alkyl, monocyclic aryl which is unsubstituted or substituted with halogen or halo(lower)alkyl, or monocyclic aryloxy which is unsubstituted or substituted with halogen or halo(lower)alkyl, or a pharmaceutically acceptable salt when R1 is hydrogen atom.
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Inventors:
UENO TAKASHI
ODA TOMIO
ODA TOMIO
Application Number:
JP5593091A
Publication Date:
June 26, 1996
Filing Date:
February 26, 1991
Export Citation:
Assignee:
UENO SEIYAKU OYO KENKYUJO KK
International Classes:
A61K31/5575; A61P9/08; A61P43/00; C07C405/00; A61K31/557; (IPC1-7): C07C405/00; C07C405/00
Other References:
FARMACO ED SCI=1976
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)