Title:
心臓血管疾患のための医薬としての、2-および/または4-置換のアンドロスタンおよびアンドロステンのアミノオキシム誘導体
Document Type and Number:
Japanese Patent JP5436432
Kind Code:
B2
Abstract:
New aminooxime derivatives at position 3 of 2- and/or 4-substituted androstanes and androstenes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.
Inventors:
Alberto Celli
Giuseppe Bianchi
Giorgio Fedrizi
Patrizia Ferrari
Mauro Gobbini
Giuseppe Marazzi
Marco Torri
Walter Cabris
Giuseppe Bianchi
Giorgio Fedrizi
Patrizia Ferrari
Mauro Gobbini
Giuseppe Marazzi
Marco Torri
Walter Cabris
Application Number:
JP2010528341A
Publication Date:
March 05, 2014
Filing Date:
September 18, 2008
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
C07J1/00; A61K31/565; A61K31/566; A61P9/04; A61P9/12
Other References:
J. Med. Chem.,2003年,46(17),pp. 3644-3654
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro