Title:
抗癌活性及び抗増殖活性を呈する２−アミノピリミジン−６−オン及び類似体
Document Type and Number:
Japanese Patent JP6936823
Kind Code:
B2
Abstract:
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
Inventors:
Kauffman, Michael Dee.
Flynn, Danielle.
Earn, Yumi
Vogueti, Lakshmi Narayana
Caldwell, Timothy Malcolm
Flynn, Danielle.
Earn, Yumi
Vogueti, Lakshmi Narayana
Caldwell, Timothy Malcolm
Application Number:
JP2019032014A
Publication Date:
September 22, 2021
Filing Date:
February 25, 2019
Export Citation:
Assignee:
Decifera Pharmaceuticals, LRC
International Classes:
C07D401/14; A61K31/513; A61K31/5377; A61P1/04; A61P11/00; A61P11/06; A61P13/12; A61P19/02; A61P19/10; A61P25/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P43/00; C07D405/14; C12N9/99
Domestic Patent References:
| JP6165314B2 |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito