Title:
2-フルオロ-1,3-ベンゾジチオール1,1,3,3-テトラオキシド誘導体、その製造方法並びにそれを用いたモノフルオロメチル基含有化合物類の製造方法
Document Type and Number:
Japanese Patent JP5534131
Kind Code:
B2
Abstract:
A 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative as a monofluoromethyl group introduction agent that is effective as an intermediate in pharmaceutical and agrochemical synthesis, a production method thereof, and a production method of a monofluoromethyl group-containing compound using this 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative are provided. The 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative represented by the following general formula (1) (wherein R1, R2, R3, and R4 each independently represent a hydrogen atom, a straight-chain or branched alkyl group having 1 to 4 carbon atoms, a straight-chain or branched alkyloxy group having 1 to 4 carbon atoms, a halogen atom, a nitro group, or a cyano group), the production method thereof, and various monofluoromethyl group-containing compounds are manufactured using this 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative as a monofluoromethylating agent.
Inventors:
Tetsuo Shibata
Application Number:
JP2009047754A
Publication Date:
June 25, 2014
Filing Date:
March 02, 2009
Export Citation:
Assignee:
National Institute of Technology Nagoya Institute of Technology
Toso-F-Tech Co., Ltd.
Toso-F-Tech Co., Ltd.
International Classes:
C07D339/06; C07C29/00; C07C33/48; C07B53/00
Domestic Patent References:
| JP2007230961A |
Other References:
Tetrahedron,(1988), Vol.44, No.22,p.6855-6860
Attorney, Agent or Firm:
Mizuno Katsufumi
Masayuki Kishida
Hiroshin Takano
Masayuki Kishida
Hiroshin Takano