Title:
α2Bアドレナリン受容体の調節剤として有用な(2-ヒドロキシ)エチル-チオウレア
Document Type and Number:
Japanese Patent JP4159363
Kind Code:
B2
Abstract:
Compounds of formula (i) and of formula (ii)wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such are useful for alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity.
Inventors:
Ken Chow
Daniel W. Gill
Wenchui Ken Fan
Michael E. Gurst
Daniel W. Gill
Wenchui Ken Fan
Michael E. Gurst
Application Number:
JP2002567898A
Publication Date:
October 01, 2008
Filing Date:
February 19, 2002
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
C07C335/14; A61K31/17; A61P29/00; C07C335/08; C07C335/10
Domestic Patent References:
| JP5117300A | ||||
| JP48029459B1 | ||||
| JP10007647A | ||||
| JP59031753A |
Other References:
Journal of Organic Chemistry,1983年,48(4),p.507-512
Attorney, Agent or Firm:
Aoyama Aoi
Yasuo Shibata
Yasuo Shibata
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