Title:
2-ピペリジルイミダゾール類から誘導されるナトリウムチャネルモジュレーター
Document Type and Number:
Japanese Patent JP2004517121
Kind Code:
A
Abstract:
The invention concerns novel sodium channel modulators derived from 2-piperidylimidazoles. The inventive compounds correspond to the general formula (I), wherein: R<1 >represents a hydrogen atom or an -X-Y-R<4 >radical wherein -X-Y represents a bond, a -CO-, -CO-O--CO-NH- or -CS-NH- radical and R<4 >represents an alkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl radical, said radicals being optionally substituted; R<2 >represents in particular an alkyl, cycloalkyl, cycloalkylalkyl or aryl radical optionally substituted; and R<3 >represents a hydrogen atom or an alkyl, cycloalkyl, cycloalkylalkyl, or aryl radical optionally substituted.
Inventors:
Big,deny
Pomier, jeac
Liberal, Anne-Marie
Pomier, jeac
Liberal, Anne-Marie
Application Number:
JP2002554678A
Publication Date:
June 10, 2004
Filing Date:
December 27, 2001
Export Citation:
Assignee:
Société de Conseille de Luciersier et Daat Precursion Syante Fitzuk
International Classes:
A61K31/415; A61K31/445; A61K31/454; A61P1/04; A61P9/06; A61P9/10; A61P25/00; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/16; A61P25/24; A61P25/28; A61P43/00; C07D401/04; (IPC1-7): A61K31/454; A61P1/04; A61P9/06; A61P9/10; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/16; A61P25/24; A61P25/28; A61P43/00; C07D401/04
Domestic Patent References:
| JP2003517479A | 2003-05-27 | |||
| JP2000515125A | 2000-11-14 | |||
| JPH11514353A | 1999-12-07 | |||
| JPH07509219A | 1995-10-12 | |||
| JPH10502670A | 1998-03-10 |
Foreign References:
| WO2000077008A2 | 2000-12-21 | |||
| WO1999064420A1 | 1999-12-16 | |||
| US5378847A | 1995-01-03 | |||
| WO2000057877A1 | 2000-10-05 | |||
| WO2001026656A2 | 2001-04-19 |
Attorney, Agent or Firm:
Shigeru Yagida
Takao Hamano
Morita Tetsuji
Takao Hamano
Morita Tetsuji