Title:
2-イミノピロリジン誘導体
Document Type and Number:
Japanese Patent JP4516922
Kind Code:
B2
Abstract:
The present invention relates to a 2-iminopyrrolidine derivative selected from the group consisting of 1-(3-tert-butyl-4-methoxy-5-morpholino-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone; 1-{3-tert-butyl-5-[4-(2-hydroxy-acetyl)piperazin-1-yl]-4-methoxyphenyl}-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-diyhdro-isoindol-2-yl)-ethanone; ethyl (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}piperazin-1-yl)-acetate; 1-(3-tert-butyl-4-methoxy-5-piperazin-1-yl-phenyl)-2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-ethanone, and (4-{3-tert-butyl-5-[2-(5,6-diethoxy-7-fluoro-1-imino-1,3-dihydro-isoindol-2-yl)-acetyl]-2-methoxy-phenyl}-piperazin-1-yl)-acetic acid; and salts thereof.
Inventors:
Shuichi Suzuki
Makoto Kotake
Mitsuaki Miyamoto
Tetsuya Kawahara
Shoji Kajiwara
Hishinuma Uharu
Kazuo Okano
Shuhei Miyazawa
Clark richard
Fumihiro Ozaki
Nobuaki Sato
Masanobu Shinoda
Atsushi Kamata
Takashi Tsukada
Fumiyoshi Matsuura
Yoshimitsu Naoe
Taro Terauchi
Yoshiaki Ohashi
Osamu Ito
Hiromu Tanaka
Warrior Takashi
Motoharu Kogushi
Kawada Riki
Toshiyuki Matsuoka
Kobayashi Hiroko
Kenichi Chiba
Kimura Akibun
Naoto Ono
Makoto Kotake
Mitsuaki Miyamoto
Tetsuya Kawahara
Shoji Kajiwara
Hishinuma Uharu
Kazuo Okano
Shuhei Miyazawa
Clark richard
Fumihiro Ozaki
Nobuaki Sato
Masanobu Shinoda
Atsushi Kamata
Takashi Tsukada
Fumiyoshi Matsuura
Yoshimitsu Naoe
Taro Terauchi
Yoshiaki Ohashi
Osamu Ito
Hiromu Tanaka
Warrior Takashi
Motoharu Kogushi
Kawada Riki
Toshiyuki Matsuoka
Kobayashi Hiroko
Kenichi Chiba
Kimura Akibun
Naoto Ono
Application Number:
JP2006041270A
Publication Date:
August 04, 2010
Filing Date:
February 17, 2006
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D209/44; A61K31/403; A61K31/4035; A61K31/4178; A61K31/4184; A61K31/422; A61K31/437; A61K31/454; A61K31/496; A61K31/5377; A61K31/538; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P19/10; A61P25/00; A61P29/00; A61P35/00; A61P43/00; C07D207/22; C07D207/24; C07D207/263; C07D207/267; C07D207/34; C07D209/52; C07D209/54; C07D209/62; C07D209/96; C07D213/73; C07D213/74; C07D233/46; C07D233/66; C07D233/88; C07D233/90; C07D235/30; C07D249/14; C07D261/14; C07D401/04; C07D401/06; C07D401/10; C07D401/12; C07D403/04; C07D403/06; C07D403/10; C07D403/12; C07D405/06; C07D409/04; C07D409/06; C07D409/10; C07D413/06; C07D413/10; C07D413/12; C07D413/14; C07D417/06; C07D417/10; C07D471/04; C07D487/04; C07D491/10; C07D498/04; C07D521/00; C07D207/26; A61K; A61P; C07D
Domestic Patent References:
| JP4244083A | ||||
| JP8225753A | ||||
| JP51125071A | ||||
| JP51022720A |
Foreign References:
| WO1996005192A1 | ||||
| WO1983002920A1 |
Other References:
Arzneim.-Forsch.,1980年,30,9,1487-1493
Chemical Abstracts,1973年,78,478,111229
J.Chem.Soc.,Chem.Commun.,1984年,17,1165-1166
Chemical Abstracts,1973年,78,478,111229
J.Chem.Soc.,Chem.Commun.,1984年,17,1165-1166
Attorney, Agent or Firm:
Yoshiki Hasegawa
Hiroto Kido
Masato Ikeda
Yoshinori Shimizu
Kimoto
Hiroto Kido
Masato Ikeda
Yoshinori Shimizu
Kimoto