Title:
CCR10アンタゴニストである2-スルホニルアミノ-4-ヘテロアリールブチロアミド
Document Type and Number:
Japanese Patent JP2011516563
Kind Code:
A
Abstract:
This invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein R1, R2, R4. Ar and Het are as defined herein. The invention also relates to methods of using the compound of formula (I) to treat a diseases and disorders that are mediated or sustained through the activity of CCR10.
Inventors:
Abbey Waldan Alisa
Corgan Derek
Choi Young Gi
Gao Dong Hong A
Goldberg Daniel Earl
Heim liter alexander
Mirror craig andrew
Ramsden Philip Dean
Smith Keenan Lana Louise
Snow Roger John
Yu Yang
Corgan Derek
Choi Young Gi
Gao Dong Hong A
Goldberg Daniel Earl
Heim liter alexander
Mirror craig andrew
Ramsden Philip Dean
Smith Keenan Lana Louise
Snow Roger John
Yu Yang
Application Number:
JP2011504143A
Publication Date:
May 26, 2011
Filing Date:
April 08, 2009
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D207/34; A61K31/438; A61K31/454; A61K31/4725; A61K31/496; A61K31/4985; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61K31/553; A61P11/06; A61P17/00; A61P29/00; A61P35/00; A61P37/08; A61P43/00; C07D401/06; C07D401/14; C07D403/12; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D491/113; C07D513/04
Domestic Patent References:
| JPH06256293A | 1994-09-13 | |||
| JP2000319250A | 2000-11-21 | |||
| JP2005521650A | 2005-07-21 | |||
| JP2008526996A | 2008-07-24 | |||
| JP2008508357A | 2008-03-21 | |||
| JP2003535079A | 2003-11-25 | |||
| JPH06256293A | 1994-09-13 | |||
| JP2000319250A | 2000-11-21 | |||
| JP2005521650A | 2005-07-21 | |||
| JP2008526996A | 2008-07-24 | |||
| JP2008508357A | 2008-03-21 | |||
| JP2003535079A | 2003-11-25 |
Foreign References:
| WO2008008374A2 | 2008-01-17 | |||
| WO2008008375A2 | 2008-01-17 | |||
| WO2008042925A1 | 2008-04-10 | |||
| WO2009038847A1 | 2009-03-26 | |||
| WO2008008374A2 | 2008-01-17 | |||
| WO2008008375A2 | 2008-01-17 | |||
| WO2008042925A1 | 2008-04-10 | |||
| WO2009038847A1 | 2009-03-26 |
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki