Title:
バルドキソロンメチルの２，２−ジフルオロプロピオンアミド誘導体、その多形体および使用方法
Document Type and Number:
Japanese Patent JP6637136
Kind Code:
B2
Abstract:
The present invention relates to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-l,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide and polymorphic forms and pharmaceutical compositions thereof for use in the treatment of cancer in combination with immunotherapy, for use in the treatment of conditions associated with oxidative stree caused by mitochondrial dysfunction and for use in the treatment of seizure disorders.
Inventors:
Anderson Eric
Decker Andrea
Ryu Xiao Fong
Decker Andrea
Ryu Xiao Fong
Application Number:
JP2018178470A
Publication Date:
January 29, 2020
Filing Date:
September 25, 2018
Export Citation:
Assignee:
Riata Pharmaceuticals, Inc.
International Classes:
C07J63/00
Domestic Patent References:
| JP6410710B2 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto