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Title:
2’3’-環状ジヌクレオチドおよびそのプロドラッグ
Document Type and Number:
Japanese Patent JP7350871
Kind Code:
B2
Abstract:
The present disclosure relates to 2′3′ cyclic phosphonate dinucleotides of Formula (I), the pharmaceutically acceptable salts, pharmaceutical composition and combinations of the substances and other medicaments or pharmaceuticals. The disclosure also relates to the compounds for the treatment or prevention of diseases or conditions modifiable by STING protein modulation, such as cancer or viral, allergic and inflammatory diseases.

Inventors:
Birx, Gabriel
Pav, Ondrej
Kostoff, Ondley
Buje Hover, Petra
Kaiser, Martin Maximilian
Shimak, Ondray
Application Number:
JP2021552846A
Publication Date:
September 26, 2023
Filing Date:
March 04, 2020
Export Citation:
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Assignee:
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I.
International Classes:
C07H21/04; A61K31/7084; A61K39/39; A61K45/00; A61P1/16; A61P31/12; A61P31/18; A61P31/20; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP2021520389A
JP2018516903A
JP2018522914A
JP2016520085A
JP2022523571A
Foreign References:
WO2017161349A1
WO2018009652A1
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK