Title:
2,4-ジアミノピリミジン誘導体
Document Type and Number:
Japanese Patent JP4362377
Kind Code:
B2
Abstract:
There are provided compounds of formula I
wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are as indicated in claim 1, useful in disorders where ZAP-70 and/or Syk inhibition plays a role or caused by a malfunction of signal cascades connected with FAK.
Inventors:
Rolf Bentelli
Gerhard Zenke
Nigel Graham Cook
Rudolf Doutara
Gephard Toma
Anette von Matt
Toshiyuki Honda
Naoko Matsuura
Kazuhiko Nonomura
Osamu Omori
Umemura Ichiro
Claus Hinterding
Cristo Papa Georges
Gerhard Zenke
Nigel Graham Cook
Rudolf Doutara
Gephard Toma
Anette von Matt
Toshiyuki Honda
Naoko Matsuura
Kazuhiko Nonomura
Osamu Omori
Umemura Ichiro
Claus Hinterding
Cristo Papa Georges
Application Number:
JP2003576410A
Publication Date:
November 11, 2009
Filing Date:
March 14, 2003
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
A61K31/505; C07D239/48; A61K31/506; A61K31/5377; A61K31/55; A61K31/635; A61K45/00; A61P1/04; A61P1/16; A61P3/10; A61P5/14; A61P9/04; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P11/06; A61P11/16; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P17/08; A61P19/02; A61P21/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P37/06; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D417/12; C07D521/00
Domestic Patent References:
| JP2005516046A | ||||
| JP2005507420A | ||||
| JP2005507380A |
Foreign References:
| US3432493 | ||||
| US5958935 | ||||
| WO2001064656A1 | ||||
| WO2000039101A1 |
Other References:
J.Med.Chem.,1966年,9,3,423-424
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima