Title:
癌の処置のためのRafキナーゼのインヒビターとしての、2,6-二置換キナゾリン、キノキサリン、キノリンおよびイソキノリン
Document Type and Number:
Japanese Patent JP2007509059
Kind Code:
A
Abstract:
New substituted quinazoline, quinoxaline, quinoline and isoquinoline compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
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Inventors:
La Mercy, Savigli
Renault, Paul A.
Sabra Manian, Sharada
Renault, Paul A.
Sabra Manian, Sharada
Application Number:
JP2006535368A
Publication Date:
April 12, 2007
Filing Date:
October 15, 2004
Export Citation:
Assignee:
Chiron Corporation
International Classes:
C07D401/12; A61K31/282; A61K31/337; A61K31/4164; A61K31/4709; A61K31/4745; A61K31/475; A61K31/498; A61K31/502; A61K31/506; A61K31/513; A61K31/517; A61K31/519; A61K31/5377; A61K31/675; A61K31/704; A61K31/7068; A61K33/24; A61K38/00; A61K39/395; A61K45/00; A61P13/08; A61P15/00; A61P35/00; A61P35/02; A61P43/00; C07D401/14; C07D405/14; G10H7/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita