Title:
2,7-SUBSTITUTED OCTAHYDRO-1H-PYRIDO[1,2-A]PYRAZINE DERIVATIVE AS LIGAND FOR SEROTONIN RECEPTOR
Document Type and Number:
Japanese Patent JP2004010619
Kind Code:
A
Abstract:
To obtain a medicinal composition comprising 2,7-substituted octahydro-1H-pyrido[1,2-a]pyrazine derivative as a ligand for serotonin receptor.
The therapeutic medicinal composition for diseases or disorders caused by serotonin system troubles is represented by formula (I) or comprises its diastereomer, optical isomer or pharmaceutically allowable salt {e.g. (7S,9aS)-7-[(3-methyl-phenoxy)methyl-2-(5-fluoropyrimidin-2-yl)-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine]}.
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Inventors:
DESAI KISHOR AMRATLAL
FLIRI ANTON FRANZ JOSEF
SANNER MARK ALLEN
FLIRI ANTON FRANZ JOSEF
SANNER MARK ALLEN
Application Number:
JP2003345180A
Publication Date:
January 15, 2004
Filing Date:
October 03, 2003
Export Citation:
Assignee:
PFIZER PROD INC
International Classes:
A61K31/495; A61K31/4985; A61K31/506; A61P1/04; A61P1/08; A61P9/10; A61P15/00; A61P15/08; A61P25/04; A61P25/06; A61P25/14; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; C07D471/04; A61P25/30; A61P35/00; A61P43/00; (IPC1-7): A61K31/4985; A61K31/506; A61P1/04; A61P9/10; A61P15/08; A61P25/04; A61P25/06; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P35/00
Attorney, Agent or Firm:
Yoshinobu Murofushi