Title:
摂食障害を治療するためのMCHアンタゴニスト(メラニン含有ホルモン)の形態で使用される3-(4-ピペリジン-1-イルメチル-フェニル)-プロピオン酸-フェニルアミド誘導体及び関連化合物
Document Type and Number:
Japanese Patent JP2007520466
Kind Code:
A
Abstract:
The invention relates to amid compounds of general formula (I), wherein groups and residuals A, B, b, W, X, Y, Z, R<1>, R<2> and R<3> have significances given in a claim 1. In addition, said invention relates to drugs containing at least one type of inventive amid. Because of the antagonist activity of an MCH-receptor, the inventive drugs are suitable for treating metabolic disturbances and/or eating disorders, in particular adiposity, bulimia, anorexia, hyperphagia and diabetes.
Inventors:
Lehmann Linz Torsten
Rustenberger Philip
Roth Gerald Jürgen
Schindler Marx
Thomas Leo
Mueller Stefan Georg
Stenkamp Dirk
Lots Ralph El Her
Rudolph Claus
Rustenberger Philip
Roth Gerald Jürgen
Schindler Marx
Thomas Leo
Mueller Stefan Georg
Stenkamp Dirk
Lots Ralph El Her
Rudolph Claus
Application Number:
JP2006546009A
Publication Date:
July 26, 2007
Filing Date:
December 17, 2004
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07C233/29; A61K31/167; A61K31/18; A61K31/351; A61K31/40; A61K31/404; A61K31/407; A61K31/415; A61K31/4164; A61K31/4196; A61K31/423; A61K31/4406; A61K31/445; A61K31/4453; A61K31/454; A61K31/4545; A61K31/47; A61K31/472; A61K31/495; A61K31/4985; A61K31/5375; A61K31/54; A61P1/14; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P5/00; A61P5/50; A61P7/12; A61P9/00; A61P9/10; A61P13/12; A61P15/00; A61P15/10; A61P19/02; A61P25/00; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P43/00; C07C233/11; C07C233/44; C07C235/38; C07C237/20; C07C255/24; C07C311/13; C07D205/04; C07D207/08; C07D207/12; C07D207/14; C07D207/20; C07D209/08; C07D211/14; C07D211/22; C07D211/26; C07D211/40; C07D211/42; C07D211/46; C07D211/48; C07D211/52; C07D211/58; C07D211/60; C07D211/62; C07D213/36; C07D213/38; C07D213/56; C07D215/38; C07D217/04; C07D221/20; C07D231/12; C07D233/56; C07D249/08; C07D263/56; C07D265/30; C07D279/12; C07D295/092; C07D295/13; C07D295/135; C07D295/14; C07D295/155; C07D309/04; C07D309/14; C07D401/06; C07D401/12; C07D403/06; C07D487/04; C07D487/08
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Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama