Title:
H3リガンドとして有用な3‐または4‐一置換フェノールおよびチオフェノール誘導体
Document Type and Number:
Japanese Patent JP4173191
Kind Code:
B2
Abstract:
The invention relates to 3- or 4-monosubstituted phenol and thiophenol derivatives of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol and thiophenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
Inventors:
Bernard Duri, Patrick
Cronin, Andrew Michael
Denny, Alexi
Denton, Stephen Martin
Jacoberg, Henri
Kemp, Mark Ian
Rotiowa, Ed Weige
Rousseau, Fiona
Cella del-Chibi, Delphine
Berne, Fabrice
Cronin, Andrew Michael
Denny, Alexi
Denton, Stephen Martin
Jacoberg, Henri
Kemp, Mark Ian
Rotiowa, Ed Weige
Rousseau, Fiona
Cella del-Chibi, Delphine
Berne, Fabrice
Application Number:
JP2007512541A
Publication Date:
October 29, 2008
Filing Date:
April 19, 2005
Export Citation:
Assignee:
Warner-Lambert Company Limited Liability Company
International Classes:
C07D309/06; A61K31/351; A61K31/397; A61K31/40; A61K31/4025; A61K31/4178; A61K31/4184; A61K31/4196; A61K31/422; A61K31/4245; A61K31/427; A61K31/437; A61K31/4433; A61K31/4439; A61K31/4453; A61K31/453; A61K31/454; A61K31/4545; A61K31/496; A61K31/4985; A61K31/501; A61K31/502; A61K31/506; A61K31/5377; A61K31/541; A61K31/55; A61K31/551; A61K31/553; A61P3/04; A61P11/00; A61P11/06; A61P11/08; A61P11/16; A61P15/10; A61P15/12; A61P25/06; A61P25/08; A61P25/14; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/16; A61P29/00; A61P37/08; A61P43/00; C07D207/08; C07D207/12; C07D213/82; C07D295/092; C07D295/12; C07D295/135; C07D295/14; C07D295/155; C07D295/26; C07D309/08; C07D405/04; C07D405/06; C07D405/12; C07D405/14; C07D413/04; C07D413/12; C07D417/04; C07D417/06; C07D417/12; C07D417/14; C07D471/04; C07D487/04
Domestic Patent References:
| JP2004509076A | ||||
| JP2004511438A | ||||
| JP2004532834A | ||||
| JP1501393A |
Foreign References:
| DE3024836A |
Other References:
Doepke, Werner et al.,"Alkaloids. 141. Structure of the alkaloid amisine",Zeitschrift fuer Chemie,1980年,Vol.20, No.8,pp.298-299,CAS RN: 76129-90-3
Attorney, Agent or Firm:
Yoshinobu Murofushi