Title:
3-アミドクロマニルスルホニル(チオ)尿素、それらの製法、それらの使用およびそれらを含有する医薬製剤
Document Type and Number:
Japanese Patent JP4242936
Kind Code:
B2
Abstract:
3-Amido-chromanylsulphonyl-urea or -thiourea derivatives of formula (I), in all stereoisomer (or mixture) forms, and their salts are new. R1 = H, alkyl, alkoxy, alkoxyalkoxy, alkylthio, F, Cl, Br, I or CF3; R2 = H, Me or Et; R3 = H or alkyl; Z = O or S; A = phenyl (optionally substituted by 1-3 halo, Me, Et, OMe or OEt), lactam residue of formula (i), 1-oxo-1,2,3,4-tetrahydroisoquinolin-2-yl, 1-oxo-perhydroisoquinolin-2-yl, 1-oxo-2,3-isoindolin-2-yl or 1-oxo-perhydroisoindolin-2-yl; B = 3-6C alkylene or 3-6C alkenylene (both optionally substituted by 1-3 alkyl); all alkyl moieties have 1-4C.
Inventors:
Heinrich Kristien Arngrat
Uwe Gerlach
Dieter Mania
Wolfgang Linz
Heinz Gegeline
Erik Claus
Uwe Gerlach
Dieter Mania
Wolfgang Linz
Heinz Gegeline
Erik Claus
Application Number:
JP31186597A
Publication Date:
March 25, 2009
Filing Date:
November 13, 1997
Export Citation:
Assignee:
Hoechst Gesellschaft Mito Beschlenktel Haftung
International Classes:
C07D311/04; A61K31/35; C07D311/58; A61K31/352; A61K31/353; A61K31/355; A61K31/40; A61K31/4025; A61P9/00; A61P9/06; C07D207/26; C07D209/34; C07D211/76; C07D217/24; C07D227/02; C07D311/16; C07D311/18; C07D311/42; C07D311/70; C07D405/12
Domestic Patent References:
| JP3066681A | ||||
| JP7304782A |
Attorney, Agent or Firm:
Chika Takagi
Tatsuo Sato
Kosuke Nishimura
Tatsuo Sato
Kosuke Nishimura