Title:
TAFIaインヒビターとしての3-(イミダゾリル)-2-アルコキシプロパン酸
Document Type and Number:
Japanese Patent JP2005520811
Kind Code:
A
Abstract:
Compounds according to formula (I) wherein n is 0-3, R<1> is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8> and R<9> are each independently selected from hydrogen and optionally substituted C 1-6 alkyl, or R<5> and R<8> are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.
Inventors:
Allerton, Charlotte, Moira Nofer
Bull, david john
Banaj, Mark Edward
Robert Majon, Robert John
Steel, john
Bull, david john
Banaj, Mark Edward
Robert Majon, Robert John
Steel, john
Application Number:
JP2003561596A
Publication Date:
July 14, 2005
Filing Date:
January 10, 2003
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
A61K31/4172; A61K31/4178; A61K31/4439; A61P7/02; A61P9/10; A61P17/02; A61P19/04; A61P29/00; A61P35/00; A61P41/00; A61P43/00; C07D233/54; C07D233/64; C07D401/04; C07D403/12; A61K; A61P; C07D; (IPC1-7): C07D233/64; A61K31/4172; A61K31/4178; A61K31/4439; A61P7/02; A61P9/10; A61P17/02; A61P19/04; A61P29/00; A61P35/00; A61P41/00; A61P43/00; C07D401/04; C07D403/12
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama