Title:
3-ACYLAMINO-3-DEOXYAMYLOSE DERIVATIVE
Document Type and Number:
Japanese Patent JPS63250394
Kind Code:
A
Abstract:
NEW MATERIAL:A compound expressed by formula I (R1 and R2 are H or together represent isopropylidene; R3 and R4 are H or together represent isopropylidene; R5 is H or alkyl; R6 is H or acyl).
EXAMPLE: 3-Deoxy-3-( 3-tetradecanoyloxytetradecanoylamino )-1,2:5,6-di-O-isopro pylidene-α-D-allofuranose.
USE: A carcinostatic agent.
PREPARATION: For example, a 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D- allofurano se expressed by formula II is condensed with a carboxylic acid expressed for formula III or active derivative thereof at 1:1W1.2 molar ratio in the presence of a dehydrating agent to afford the aimed 3-acylamino-3- deoxy-1,2:5,6-di-O-isorpropylidene-α-D-allofuranose expressed by formula IV.
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Inventors:
TOKISAWA MINORU
OTSUKA MARI
IRINODA KAZUHIKO
ISHIZEKI SEIJI
ISHII FUMIO
KUKITA KENICHI
MATSUDA HIDEAKI
KATORI TATSUHIKO
OTSUKA MARI
IRINODA KAZUHIKO
ISHIZEKI SEIJI
ISHII FUMIO
KUKITA KENICHI
MATSUDA HIDEAKI
KATORI TATSUHIKO
Application Number:
JP8258087A
Publication Date:
October 18, 1988
Filing Date:
April 03, 1987
Export Citation:
Assignee:
SS PHARMACEUTICAL CO
International Classes:
C07H13/06; A61K31/70; A61K31/7024; A61P35/00; C07H9/04; C07H13/04; (IPC1-7): A61K31/70; C07H13/06
Attorney, Agent or Firm:
Ariga Miyuki