Title:
3-BROMO-3-BROMOMETHYLPHTHALIDE DERIVATIVE
Document Type and Number:
Japanese Patent JPS5498753
Kind Code:
A
Abstract:
NEW MATERIAL:3-Bromo-3-bromomethyl-6-ethoxycarbonyl-5,7-dimethylphthalide of formula I.
USE: An intermediate for 7-ethoxycarbonyl-4-hydroxymethyl-6,8-dimethyl-1-phthalazone that is effective in preventing disorders in arteriosclerosis and thrombosis.
PREPARATION: Bromine is made to act on 6-ethoxycarbonyl-3-hydroxy-3,5,7-trimethylphthalide of formula II in an adquate solvent to prepare the objective compound of formula I. The anhydrous condition increases the yield.
Inventors:
MORIGUCHI SOYAO
IWASAKI HIROKAZU
SOYA SUMIO
GOTOU KATSUHIKO
IWASAKI HIROKAZU
SOYA SUMIO
GOTOU KATSUHIKO
Application Number:
JP367978A
Publication Date:
August 03, 1979
Filing Date:
January 19, 1978
Export Citation:
Assignee:
SHOWA DENKO KK
MASAYUKI ISHIKAWA
MASAYUKI ISHIKAWA
International Classes:
C07D307/89; (IPC1-7): C07D307/89