3’-エチニルシチジン誘導体

Japanese Patent JP4989649

B2

To provide a compound which exhibits excellent anti-tumor activity and excellent oral absorption and which is a useful anti-tumor drug. The invention provides a 3'-ethynylcytidine derivative represented by formula (1): (wherein X represents a (substituted) alkylcarbonyl group, a (substituted) alkoxycarbonyl group, or a hydrogen atom; one of Y and Z represents a hydrogen atom or a group represented by (R 1 ) (R 2 ) (R 3 )Si- and the other represents a group represented by (R 4 ) (R 5 ) (R 6 )Si-; and R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 each represent a (substituted) alkyl group, a (substituted) cyclic alkyl group, or a (substituted) aryl group) or a salt thereof.

JP2714964	INDUSTRIAL APPLICABILITY A method of measuring one or more components of a reaction between a specifically bound protein and a corresponding binding substance in one test sample using at least one labeled component. Methods for preparing labeled ingredients, and test kits for measuring immune components
WO/1997/016456	NOVEL NUCLEOSIDE DERIVATIVES AND PROCESS FOR PREPARING THE SAME
WO/2008/025886	METAL CHELATES AND CHELATING AGENTS CONTAINING TRIAZOLYL SUBUNITS

Motoaki Tanaka
Masakazu Fukushima

JP2008526678A

August 01, 2012

July 23, 2007

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Taiho Pharmaceutical Co., Ltd.
Tasaki Sasaki
Akira Matsuda

C07H23/00; A61K31/7068; A61P35/00; A61P35/02

J. Med. Chem.,1998年,Vol.41, No.15,pp.2892-2902

Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto

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