Title:
CXCケモカインレセプターアンタゴニストとしての3,4-二置換シクロブテン-1,2-ジオン
Document Type and Number:
Japanese Patent JP2004529911
Kind Code:
A
Abstract:
There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or isomer of said compound or of said prodrug, which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
Inventors:
Taveras, Arthur Gee.
Aki, Cynthia Jay.
Bond, Richard W.
Chao, The Amping
Dwyer, michael
Ferreira, Johan Ay.
Pachiter, Jonathan
Baldwin, John Jay.
Kaiser, Burned
Li
Merit, Jay Robert
Nelson, Kingsley H., Junior
Rocco, Laura El.
Aki, Cynthia Jay.
Bond, Richard W.
Chao, The Amping
Dwyer, michael
Ferreira, Johan Ay.
Pachiter, Jonathan
Baldwin, John Jay.
Kaiser, Burned
Li
Merit, Jay Robert
Nelson, Kingsley H., Junior
Rocco, Laura El.
Application Number:
JP2002576189A
Publication Date:
September 30, 2004
Filing Date:
February 01, 2002
Export Citation:
Assignee:
Schering Corporation
International Classes:
A61K31/136; A61K31/166; A61K31/167; A61K31/18; A61K31/192; A61K31/198; A61K31/216; A61K31/24; A61K31/27; A61K31/277; A61K31/36; A61K31/397; A61K31/40; A61K31/4174; A61K31/4184; A61K31/4192; A61K31/426; A61K31/433; A61K31/4402; A61K31/4406; A61K31/445; A61K31/4453; A61K31/495; A61K31/505; A61K31/5375; A61P1/00; A61P7/00; A61P7/02; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/08; A61P25/28; A61P29/00; A61P31/04; A61P33/06; A61P37/02; A61P37/08; A61P43/00; C07C221/00; C07C225/20; C07C229/42; C07C229/64; C07C237/36; C07C237/44; C07C255/58; C07C255/59; C07C271/20; C07C311/08; C07C311/21; C07D205/04; C07D207/08; C07D207/16; C07D211/60; C07D213/74; C07D213/89; C07D231/38; C07D231/44; C07D233/64; C07D235/06; C07D239/42; C07D249/18; C07D277/20; C07D277/24; C07D277/28; C07D277/42; C07D277/56; C07D285/08; C07D295/12; C07D295/13; C07D295/135; C07D295/16; C07D295/192; C07D295/20; C07D295/205; C07D317/66; C07D333/38; C07D403/12; C07D405/12; (IPC1-7): C07C221/00; A61K31/136; A61K31/166; A61K31/167; A61K31/18; A61K31/192; A61K31/198; A61K31/216; A61K31/24; A61K31/27; A61K31/277; A61K31/36; A61K31/397; A61K31/40; A61K31/4174; A61K31/4184; A61K31/4192; A61K31/426; A61K31/433; A61K31/4402; A61K31/4406; A61K31/445; A61K31/4453; A61K31/495; A61K31/505; A61K31/5375; A61P1/00; A61P7/00; A61P7/02; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/08; A61P25/28; A61P29/00; A61P31/04; A61P33/06; A61P37/02; A61P37/08; A61P43/00; C07C229/42; C07C229/64; C07C237/36; C07C237/44; C07C255/58; C07C255/59; C07C271/20; C07C311/08; C07C311/21; C07D207/08; C07D207/16; C07D211/60; C07D213/74; C07D213/89; C07D231/44; C07D233/64; C07D235/06; C07D239/42; C07D249/18; C07D277/20; C07D277/24; C07D277/42; C07D285/08; C07D295/12; C07D295/16; C07D295/20; C07D317/66; C07D333/38; C07D403/12; C07D405/12
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita