Title:
エンドセリン受容体アンタゴニストとしての4-(ヘテロシクリルスルホンアミド)-5-メトキシ-6-(2-メトキシフェノキシ)-2-フェニル-又はピリジルピリミジン類
Document Type and Number:
Japanese Patent JP3983477
Kind Code:
B2
Abstract:
The compounds of formula (I)wherein R1, R2 and X have the significance as given in the description, are inhibitors of endothelin receptors and can therefore be used for the treatment of disorders which are associated with abnormal vascular tone and endothelial dysfunction.
Inventors:
Broy, Volker
Core solo, philip
Hoover, Rolf
Nidar, Werner
Ramie, Henri
Lou, Sebastian
Hans Peter, Wessel
Core solo, philip
Hoover, Rolf
Nidar, Werner
Ramie, Henri
Lou, Sebastian
Hans Peter, Wessel
Application Number:
JP2000593603A
Publication Date:
September 26, 2007
Filing Date:
January 10, 2000
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D401/04; A61K31/505; A61K31/506; A61P1/04; A61P1/16; A61P1/18; A61P3/04; A61P7/02; A61P9/00; A61P9/04; A61P9/06; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P15/10; A61P25/06; A61P27/06; A61P35/00; A61P37/02; A61P43/00; C07D401/12; C07D401/14; C07D405/14; C07D413/14; C07D417/12; C07D417/14; C07D213/00; C07D239/00; C07D271/00; C07D277/00
Domestic Patent References:
| JP8208625A | ||||
| JP10509182A |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda