Title:
[(4-オキソ-4H-クロメン-3-イル)ヒドロキシメチル]または[(4-オキソ-4H-クロメン-3-イル)メチル]ホスホン酸誘導体
Document Type and Number:
Japanese Patent JP2010508247
Kind Code:
A
Abstract:
[(4-Oxo-4H-chromen-3-yl)-hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)-methyl]-phosphoric acid derivatives (I) and their salts, are new. [(4-Oxo-4H-chromen-3-yl)-hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)-methyl]-phosphoric acid derivatives of formula (I) and their salts, are new. R 1>, R 3>H, OH or 1-8C alkoxy; R 4>H, 1-4C alkyl, OH or 1-8C alkoxy; R 5>H or OH (preferred); and R 6>H or 1-18C alkyl. Where R 1>-R 4> is not hydrogen at the same time. Independent claims are included for: (1) the preparations of (I); and (2) a preparation containing (I). [Image] ACTIVITY : Nootropic; Dermatological. MECHANISM OF ACTION : Histidinde-carboxylase inhibitor; Protein inhibitor; Elastase inhibitor; Aldosereductase hyaluronidase inhibitor.
Inventors:
Corolla, Christoph
Buchholz, Helwig
Buchholz, Helwig
Application Number:
JP2009533683A
Publication Date:
March 18, 2010
Filing Date:
October 04, 2007
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07F9/655; A23K1/16; A23L1/30; A23L33/155; A61K8/55; A61K31/665; A61P17/16; A61P39/06; A61Q19/08; C09K15/32
Domestic Patent References:
| JP2003286413A | 2003-10-10 | |||
| JPH10237081A | 1998-09-08 | |||
| JPH09165394A | 1997-06-24 | |||
| JPH06228170A | 1994-08-16 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa
Noriki Mitsuhashi
Takakawara Yoshiko
Noriki Mitsuhashi
Takakawara Yoshiko