高血圧の処置のためのレニン阻害剤としての5-アミノ-4-ヒドロキシ-7-(1H-インドールメチル)-8-メチルノンアミド誘導体

Title:

高血圧の処置のためのレニン阻害剤としての5-アミノ-4-ヒドロキシ-7-(1H-インドールメチル)-8-メチルノンアミド誘導体

Document Type and Number:

Japanese Patent JP2007529474

Kind Code:

A

Abstract:

The application relates to novel alkanamides of the general formula where X, R 1 , R 2 , R 3 , R 4 and R 5 are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, especially as renin inhibitors.

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Inventors:

Herolt, peter
Stutz, Stephan
Mar, robert
Tincke, Vincenzo
Stoyanovich, Alexander
Yottaland, Natalie
Kvilmbach, Michael
Bernke, dirk
Marzi, Christiane

Application Number:

JP2007503352A

Publication Date:

October 25, 2007

Filing Date:

March 17, 2005

Export Citation:

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Assignee:

SPEEDEL EXPERIMENTA AG

International Classes:

C07D209/18; A61K31/405; A61K31/4439; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P27/06; C07C237/06; C07C237/22; C07D209/12; C07D209/20; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D417/12

Domestic Patent References:

JPH0881430A	1996-03-26
JPH0827079A	1996-01-30
JPH08231485A	1996-09-10
JPH08176087A	1996-07-09

Foreign References:

WO2003103653A1

2003-12-18

Attorney, Agent or Firm:

Hajime Tsukuni
Fumio Shinoda

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