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Title:
A 5-Culver Moyle Adamantane - 2- Ylamide derivative, its pharmacologically permissible salt, and a manufacturing method for the same
Document Type and Number:
Japanese Patent JP6045573
Kind Code:
B2
Abstract:
Provided are a novel derivative of 5-carbamoyl adamantan-2-yl amide of Formula (I), or a pharmaceutically acceptable salt thereof, and a pharmaceutical use thereof for inhibiting the activity of 11β-hydroxystreroid dehydrogenase type 1 (11b-HSD1) or for preventing and/or treating various diseases mediated by 11β-hydroxystreroid dehydrogenase type 1.

Inventors:
Jung, Kumin
Ryu, Jeongho
Lee, Yun Kyung
Moon, disk
Lee, Hye Sung
Lee, Song Jung
Oh, Gyeongsuk
Application Number:
JP2014514817A
Publication Date:
December 14, 2016
Filing Date:
June 11, 2012
Export Citation:
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Assignee:
SK by Offer Mathewicals Company Limited
International Classes:
C07D207/34; A61K31/341; A61K31/381; A61K31/40; A61K31/42; A61K31/422; A61K31/4418; A61K31/4425; A61K31/47; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P19/02; A61P43/00; C07D213/81; C07D213/89; C07D215/48; C07D215/60; C07D261/18; C07D307/68; C07D333/38; C07D401/04; C07D409/04; C07D413/04; C07D413/12; C07D417/04
Domestic Patent References:
JP2010180178A
Foreign References:
WO2011139107A1
WO2008142986A1
WO2007114124A1
WO2011049520A1
WO2011059021A1
WO2011068927A1
Attorney, Agent or Firm:
Ryu Iwatani