Title:
5-LIPOXYGENASE PROMOTER
Document Type and Number:
Japanese Patent JPS6429311
Kind Code:
A
Abstract:
PURPOSE: To obtain a 5-lipoxygenase promoter useful for improving immune depression in cancers, various virus infections, containing a diterpene compound as an active ingredient.
CONSTITUTION: A compound shown by formula I [A is group shown by formula II, III, IV or V (X is halogen); R1 is -H, -OH, -CH2, -CH2OH or CH2OAC (AC is acetyl); R2 is -H, -OH, -CH2 or -OAC=O; R3 is -H, -OH or OAC] is blended with a conventional drug carrier or excipient and pharmaceutically manufactured to give the aimed substance. The aimed substance can be prepared into a dosage form such as tablet, sugar-coated tablet, powder, capsule, granule, suspension, emulsion or injection.
Inventors:
ARAI JUNICHIRO
IZUMI KAZUHIRO
AOSHIMA JIRO
KUSUNOKI SHINICHIRO
IZUMI KAZUHIRO
AOSHIMA JIRO
KUSUNOKI SHINICHIRO
Application Number:
JP18345687A
Publication Date:
January 31, 1989
Filing Date:
July 24, 1987
Export Citation:
Assignee:
ADVANCE CO LTD
International Classes:
C07D307/58; A61K31/34; A61K31/341; A61P37/00; A61P43/00; C07D407/06; (IPC1-7): A61K31/34; C07D307/58; C07D407/06