5-THIA-ω-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVE

Title:

5-THIA-ω-SUBSTITUTED PHENYL-PROSTAGLANDIN E DERIVATIVE

Document Type and Number:

Japanese Patent JP3703004

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To obtain a new 5-thia-ω-substituted phenyl-prostaglandin E derivative.
SOLUTION: This 5-thia-ω-substituted phenyl-prostaglandin E derivative is a compound expressed by formula I {R1 is hydroxyl, a 1-6C alkyloxy or NR6R7 (R6, R7 are each independently H or a 1-4C alkyl); R2 is oxo, a halogen or OCOR8 [R8 is a 1-4C alkyl, phenyl or phenyl (1-4C alkyl)]; R3 is H or hydroxyl, R4a and R4b are each independently H or a 1-4C alkyl; R5 is a substituted phenyl).

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Inventors:

Toru Maruyama
Shuichi Ouchida

Application Number:

JP2000104840A

Publication Date:

October 05, 2005

Filing Date:

July 14, 1999

Export Citation:

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Assignee:

Ono Pharmaceutical Co., Ltd.

International Classes:

A61K47/40; A61K31/5575; A61P1/04; A61P1/16; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P25/00; A61P29/00; A61P37/00; C07C405/00; C08B37/16; (IPC1-7): C07C405/00; A61K31/5575; A61K47/40; A61P1/04; A61P1/16; A61P9/10; A61P9/12; A61P11/06; A61P13/12; A61P25/00; A61P29/00; A61P37/00; C08B37/16

Domestic Patent References:

JP3223244A
JP63079870A

Attorney, Agent or Firm:

Kunihisa Landlord

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