Title:
5,6-ジメチルチエノ[2,3-d]ピリミジン誘導体、その製造方法及びそれを含む抗ウイルス用薬学的組成物
Document Type and Number:
Japanese Patent JP4767321
Kind Code:
B2
Abstract:
Disclosed herein are 5,β-dimethylthieno[2,3-d]pyrimidine derivatives useful as antiviral agents. More particularly, disclosed are 5,β-dimethylthieno[2,3-djpyrimidine derivatives represented by Formula 1, having an excellent inhibitory effect on the proliferation of hepatitis C virus (HCV), pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition for the prevention and treatment of hepatitis C virus (HCV), containing, as active ingredients, these compounds. The 5,6-dimethylthieno[2,3-d]pyrimidine derivatives represented by Formula 1 have an excellent effect of inhibiting the proliferation of hepatitis C virus and also have low toxicity. Thus, these compounds are available as agents for the prevention and treatment of hepatitis C.
Inventors:
Han Cheol Cue
Young Jung Hyuk
Kim Nam-Do
Kim Chin-Ah
Young Jung Hyuk
Kim Nam-Do
Kim Chin-Ah
Application Number:
JP2008532154A
Publication Date:
September 07, 2011
Filing Date:
September 23, 2005
Export Citation:
Assignee:
Equispharm Corporation Limited
International Classes:
C07D495/04; A61K31/5377; A61P31/14
Domestic Patent References:
| JPS58225089A | 1983-12-27 | |||
| JPS5268197A | 1977-06-06 |
Foreign References:
| US6133271A | 2000-10-17 |
Attorney, Agent or Firm:
Eiji Saegusa
Kenji Saito
Mutsuko Nakano
Masahito Hayashi
Kenji Saito
Mutsuko Nakano
Masahito Hayashi