6-アルコキシアルキルエストラジオール誘導体およびその使用

Title:

6-アルコキシアルキルエストラジオール誘導体およびその使用

Document Type and Number:

Japanese Patent JP5290189

Kind Code:

B2

Abstract:

A compound having the structure : wherein R₁, R₂, R₃, R₄, R₅, R₆, R₇ and R₉ are independently hydrogen, C₁to C₆ alkyl or substituted alkyl, halogen, sulfate or glucuronide moieties; the ---- symbol represents either a single or a double bond and when the ---- symbol is a double bond and forms a keto group at position 3 or 17, then no R₇ or R₆is present, respectively; the symbol --- represent the presence or absence of a bond at position 10; and the ~~~ symbol represents any type of bond regardless of the stereochemistry. The invention also embraces the enantiomers, other stereochemical isomers, hydrates, solvates, tautomers and pharmaceutically acceptable salts of said compounds.

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Inventors:

Jamer, jamer

Application Number:

JP2009539479A

Publication Date:

September 18, 2013

Filing Date:

November 29, 2007

Export Citation:

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Assignee:

ENDECE,LLC

International Classes:

C07J1/00; A61K31/567; A61P35/00

Domestic Patent References:

JP2009533392A
JP2009510125A

Foreign References:

DD258820A1
WO2005070951A1

Other References:

Steroids,1993年,58,527-532
Helvetiva Chimica Acta,1973年,56(7),2396-2404

Attorney, Agent or Firm:

Hatta International Patent Corporation

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