Title:
６，７，８，９−テトラヒドロ−５Ｈ−１，４，７，１０ａ−テトラアザ−シクロヘプタ［ｆ］インデン誘導体、これらの化合物を含有する医薬組成物、それらの使用及びそれらの調製方法
Document Type and Number:
Japanese Patent JP5747331
Kind Code:
B2
Abstract:
The present invention relates to compounds defined by formula (I), wherein the groups X, Y, W and R1 to R4 are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are agonists of the 5-HT2C receptor, and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this receptor, such as metabolic and CNS-related disorders.
Inventors:
Muller, Stephan-Georg
Brown, Christopher John
Heifetz, alexander
Nosse, Bernd
Prestor, Jurgen
Prevaux, Natasha
Rudolph, Claus
Shearer, Stephan
Schindler, Marx
Dirk, Stenkamp
Thomas, Leo
Thailand, Heather
Brown, Christopher John
Heifetz, alexander
Nosse, Bernd
Prestor, Jurgen
Prevaux, Natasha
Rudolph, Claus
Shearer, Stephan
Schindler, Marx
Dirk, Stenkamp
Thomas, Leo
Thailand, Heather
Application Number:
JP2011537977A
Publication Date:
July 15, 2015
Filing Date:
November 26, 2009
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D487/14; A61K31/55; A61K31/551; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P11/16; A61P13/10; A61P15/00; A61P19/02; A61P19/06; A61P25/00; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/36; A61P35/00; C07D519/00
Domestic Patent References:
| JP2008505102A | ||||
| JP2000186090A | ||||
| JP2005508969A | ||||
| JP2008540368A |
Foreign References:
| WO2008117169A1 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fusayuki Saito
Fusayuki Saito