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Title:
8-AZA, 6-AZA, AND 6,8-DIAZA-1,4-DIHYDROQUINOXALINE-2,3-DIONE COMPOUNDS
Document Type and Number:
Japanese Patent JP2005247864
Kind Code:
A
Abstract:

To provide a method for treating or preventing neuron loss, neurodegenerative diseases, and the injurious effects of excitatory amino acid overstimulation.

This medicinal composition contains a compound represented by formula [R4, R5 and R6 are each independently H, amino, a halogen atom or the like; Rc and Rd are each independently H, OH, amino or the like; (n) is 0 or 1] or its pharmaceutically acceptable salt.


Inventors:
CAI SUI XIONG
WEBER ECKARD
KEANA JOHN F W
Application Number:
JP2005121174A
Publication Date:
September 15, 2005
Filing Date:
April 19, 2005
Export Citation:
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Assignee:
ACEA PHARM INC
UNIV CALIFORNIA
OREGON STATE
International Classes:
A61K31/495; A61K31/4985; A61K31/519; A61P9/10; A61P21/00; A61P21/02; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/20; A61P25/22; A61P25/28; C07D487/04; A61P25/36; A61P43/00; C07D471/04; C07D475/00; (IPC1-7): C07D471/04; A61K31/4985; A61K31/519; A61P9/10; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P25/14; A61P25/22; A61P25/28; A61P25/36; C07D487/04
Domestic Patent References:
JPS55115875A1980-09-06
JPS574988A1982-01-11
JPH04178385A1992-06-25
JPH05310732A1993-11-22
JPH02290852A1990-11-30
JPS61280483A1986-12-11
Foreign References:
WO1992007847A11992-05-14
WO1992019602A11992-11-12
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura