Title:
ＡＰＪ受容体アゴニストおよびその使用
Document Type and Number:
Japanese Patent JP6710253
Kind Code:
B2
Abstract:
The application is directed to APJ receptor agonist analogs having increased stability relative to the wild type apelin-13 and methods of using the agonist analogs. The analogs can be used, inter alia, in cardiac disorders such as heart failure.
Inventors:
Jerry Ryan Holder
Raspberry Swaminas
Leslie P. Miranda
Jennifer aral
Elizabeth M. Doherty
Thomas Nixie
Raspberry Swaminas
Leslie P. Miranda
Jennifer aral
Elizabeth M. Doherty
Thomas Nixie
Application Number:
JP2018198955A
Publication Date:
June 17, 2020
Filing Date:
October 23, 2018
Export Citation:
Assignee:
Amjien Incorporated
International Classes:
A61K38/08; C07K19/00; A61K38/16; A61K38/17; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12
Domestic Patent References:
| JP2003512011A |
Foreign References:
| WO2012125408A1 |
Other References:
ChemMedChem (Epub Dec 2011) vol.7, issue 2, p.318-325
Russian Journal of Bioorganic Chemistry,2012年 1月28日,Vol.38, No.1,p.40-51,URL,http://dx.doi.org/10.1134/S1068162012010177
Russian Journal of Bioorganic Chemistry,2012年 1月28日,Vol.38, No.1,p.40-51,URL,http://dx.doi.org/10.1134/S1068162012010177
Attorney, Agent or Firm:
Kawaguchi International Patent Office