Title:
ＡＴＦ５ペプチド多様体及びそれらの使用
Document Type and Number:
Japanese Patent JP6971508
Kind Code:
B2
Abstract:
Provided are ATF5 peptides having a truncated ATF5 leucine zipper region and, optionally, a cell-penetrating region, compositions comprising the ATF5 peptides, and methods of inhibiting proliferation of and promoting cytotoxicity in a neoplastic cell using the ATF5 peptides.
Inventors:
Kappel, Barry Jay
Meltuka, Jean
Rotoro, Jimmy Andrew
Meltuka, Jean
Rotoro, Jimmy Andrew
Application Number:
JP2020557117A
Publication Date:
November 24, 2021
Filing Date:
January 03, 2019
Export Citation:
Assignee:
Sapiens Therapeutics Incorporated
International Classes:
C12N15/12; A61K38/02; A61P35/00; A61P43/00; C07K14/47; C07K19/00; C12N15/62; C12Q1/02
Domestic Patent References:
| JP2016516669A |
Foreign References:
| US20150094271 |
Other References:
The Journal of Biological Chemistry,2014年,Vol.289, No.7,pp.3888-3900
Clinical Cancer Research,2016年,Vol.22, No.18,pp.4698-4711
Clinical Cancer Research,2016年,Vol.22, No.18,pp.4698-4711
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Toshitaka Tsurugi
Toru Miyamae
Motoharu Nakanishi
Toshitaka Tsurugi
Previous Patent: Integrated height adjustment washbasin
Next Patent: All-weather batting practice machine
Next Patent: All-weather batting practice machine