ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF

Title:

ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF

Document Type and Number:

Japanese Patent JP2017019859

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide acetaminophen conjugates, and to provide compositions and methods of use thereof.SOLUTION: Acetaminophen conjugates are provided, which have an acetaminophen moiety covalently linked to a second moiety. The conjugates provided may have one or more advantageous properties, including increased water solubility as compared to acetaminophen, reduced toxicity profile as compared to acetaminophen and an altered pharmacokinetic profile. Formulations comprising the conjugates are also provided, as well as methods of using the conjugates and kits comprising the conjugates.SELECTED DRAWING: None

More Like This:

JP4065881	Compounds with physiological refreshing effects
JPH07179402	SUBSTITUTED BENZENE DERIVATIVE, ITS PRODUCTION AND PEST-CONTROLLING AGENT CONTAINING THE SAME
WO/2021/108282	AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS

Inventors:

BLEY KEITH R
BERND JANDELEIT

Application Number:

JP2016204398A

Publication Date:

January 26, 2017

Filing Date:

October 18, 2016

Export Citation:

Click for automatic bibliography generation Help

Assignee:

ACORDA THERAPEUTICS INC

International Classes:

C07C329/06; A61K31/265; A61P9/10; A61P25/00; A61P25/04; A61P29/00; C07C313/04

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

Previous Patent: JP2017019858

Next Patent: USE OF GDF TRAP TO INCREASE RED BLOOD CELL LEVEL