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Title:
成長因子レベルを調節可能な活性化血小板組成物
Document Type and Number:
Japanese Patent JP7248721
Kind Code:
B2
Abstract:
To provide methods and systems for generating a tunable or customizable activated product composition.SOLUTION: A method for releasing growth factors comprises: positioning a sample with respect to electrodes of a pulse generating apparatus; specifying a set of electric pulse parameters, where different parameter values yield different levels of one or more growth factors in an activated product composition; and exposing the sample to one or more electric pulses generated in accordance with the parameter values, where the sample, when exposed to the one or more electric pulses, yields the activated product composition having levels of the one or more growth factor determined at least in part by the set of electric pulse parameters. The sample comprises one of a platelet-rich plasma sample, a platelet suspension and a whole blood sample.SELECTED DRAWING: Figure 1

Inventors:
Neclaes, Vasile Bogdan
Bethera, Juan Jose
Morten, Christine Angela
Tres, Andrew Solids
Caiafa, Antonio
Application Number:
JP2021023806A
Publication Date:
March 29, 2023
Filing Date:
February 17, 2021
Export Citation:
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Assignee:
GENERAL ELECTRIC COMPANY
International Classes:
C12Q1/02; C12M1/42; C12N13/00
Domestic Patent References:
JP2007007430A
Foreign References:
US20140363412
WO2015108619A1
WO2015108778A1
WO2004108146A1
Other References:
Arch. Biochem. Biophys.,2008年,vol.471,p.240-248
EWMA J.,2015年,vol.15 no.1,p.15-19
Attorney, Agent or Firm:
Kazuya Sekiguchi