Title:
ACTIVE COMPOUND, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
Document Type and Number:
Japanese Patent JPS643185
Kind Code:
A
Abstract:
NEW MATERIAL: The (S)-isomer of a compd. of formula I (where OH in the chain may be in the form of its o-acyl, phosphate, cyclic acetal or cyclic carbonate deriv.) or a mixture of the (S)-isomer with <45 wt.% of the corresponding (R)-isomer.
EXAMPLE: (S)-2-amino-9-(2,3-dihydroxyprop-1-oxy)purine.
USE: A viral infection treating agent.
PROCESS: The (S)-isomer of the compd. of the formula I is obtd. by reducing a compd. of formula II (where each of Ra and Rb is H or a protective group) and optionally converting Ra and/or Rb into OH or optionally forming a deriv. and/or a salt of the resultant compd.
Inventors:
MAIKERU REIMONDO HAANDEN
POORU GURAHAMU WAIATSUTO
SUCHIYUAATO BEERII
POORU GURAHAMU WAIATSUTO
SUCHIYUAATO BEERII
Application Number:
JP13130888A
Publication Date:
January 06, 1989
Filing Date:
May 28, 1988
Export Citation:
Assignee:
BEECHAM GROUP PLC
International Classes:
A61K31/52; A61P31/12; C07C67/00; C07C239/00; C07D317/16; C07C239/20; C07D317/18; C07D473/32; (IPC1-7): A61K31/52; C07C83/02; C07D317/16; C07D473/32
Attorney, Agent or Firm:
Masamitsu Akizawa (1 person outside)
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