Title:
肥満、糖尿病及び脂質異常を治療するためのアシルスルファミド類
Document Type and Number:
Japanese Patent JP4181408
Kind Code:
B2
Abstract:
A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment, control or prevention of obesity, non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, vascular restenosis, inflammation, and other PPAR gamma mediated diseases, disorders and conditions.
Inventors:
AJ Bryan
Acton, Jiyoung Jei, The Third
Acton, Jiyoung Jei, The Third
Application Number:
JP2002560584A
Publication Date:
November 12, 2008
Filing Date:
January 25, 2002
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
A61K45/00; C07C307/06; A61K31/18; A61K31/222; A61K31/235; A61K31/27; A61P1/04; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P5/28; A61P5/50; A61P9/00; A61P9/10; A61P9/12; A61P15/00; A61P17/00; A61P17/06; A61P17/10; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07C311/18; C07C335/26; C07C381/08; C07D211/26; F16M11/00; F24H9/06
Foreign References:
| WO2001000579A1 | ||||
| WO2000008002A1 | ||||
| WO1999038845A1 | ||||
| WO1998039006A1 | ||||
| WO1998025598A1 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura