Title:
アダマンチルメチルアミン誘導体およびその医薬としての使用
Document Type and Number:
Japanese Patent JP7228897
Kind Code:
B2
Abstract:
The present invention provides a pharmaceutical composition for treating or preventing a cognitive disease or disorder, comprising a compound represented by Formula (I), an enantiomer thereof, a diastereomer thereof, or a pharmaceutically acceptable salt thereof.
Inventors:
Shigeki Moriguchi
Koji Fukunaga
Yoshiharu Iwabuchi
Koji Fukunaga
Yoshiharu Iwabuchi
Application Number:
JP2019534577A
Publication Date:
February 27, 2023
Filing Date:
August 02, 2018
Export Citation:
Assignee:
Tohoku University
International Classes:
C07C211/29; A61K31/137; A61K31/165; A61K31/17; A61K31/18; A61K31/222; A61K31/27; A61K31/4402; A61K31/4406; A61P3/10; A61P25/16; A61P25/18; A61P25/28; A61P43/00; C07C215/28; C07C233/13; C07C233/60; C07C233/66; C07C235/06; C07C237/06; C07C271/12; C07C275/28; C07C309/66; C07C309/73; C07C311/03; C07C311/16; C07C321/28; C07D213/40; C07D213/81
Domestic Patent References:
| JP6808154B2 | ||||
| JP2010519304A | ||||
| JP2008525425A |
Foreign References:
| WO2017131097A1 | ||||
| CN107556244A |
Other References:
RN:1990660-80-4~1499084-76-2,Registry(STN),2016年09月11日,Retrieved from STN international [online] ;retrieved on 10 October 2018
LACHENICHT, S. et al.,Synthesis of Modified 4H-1,2,4-Benzothiadiazine-1,1-dioxides and Determination of their Affinity and,ChemMedChem,2009年,Vol.4, No.11,p.1850-1858,化合物12e,13k
MORIGUCHI, S. et al.,Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer',Molecular Psychiatry,2016年,advance online publication,p.1-11,Whole document
TERAMOTO, N.,Pharmacological Profile of U-37883A, a Channel Blocker of Smooth Muscle-Type ATP-Sensitive K+ Channe,Cardiovascular Drug Reviews,2006年,Vol.24, No.1,p.25-32,Whole document
LACHENICHT, S. et al.,Synthesis of Modified 4H-1,2,4-Benzothiadiazine-1,1-dioxides and Determination of their Affinity and,ChemMedChem,2009年,Vol.4, No.11,p.1850-1858,化合物12e,13k
MORIGUCHI, S. et al.,Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer',Molecular Psychiatry,2016年,advance online publication,p.1-11,Whole document
TERAMOTO, N.,Pharmacological Profile of U-37883A, a Channel Blocker of Smooth Muscle-Type ATP-Sensitive K+ Channe,Cardiovascular Drug Reviews,2006年,Vol.24, No.1,p.25-32,Whole document
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Takuji Terachi
Toru Miyamae
Motoharu Nakanishi
Takuji Terachi
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