Title:
Ｋｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子発現の活性化用剤
Document Type and Number:
Japanese Patent JP7201164
Kind Code:
B2
Abstract:
To provide agents for activating biodefense genes by a Keap1-Nrf2 system, which are safe to take for a long time, can be used as a food and drink, and have excellent active action of biodefense genes by the Keap1-Nrf2 system.SOLUTION: Provided are an agent for activating biodefense genes by a Keap1-Nrf2 system containing as an active ingredient Barley young leaves containing a specific component, or a processed product thereof, and a food or drink comprising the activating agent. Such activating agent and food and drink enhance the antioxidant biodefense and detoxification ability of a living body because of having the action of activating biodefense genes by the Keap1-Nrf2 system, and is expected to have effects such as the prevention or improvement (treatment) of various diseases involving oxidative stress, and the prevention or improvement (treatment) of a disease or condition (symptom) caused by reduced activity of the biodefense gene expression by the Keap1-Nrf2 system.SELECTED DRAWING: None
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Inventors:
惠 淑萍
Hitoshi Chiba
Hirotoshi Fuda
Chen Zhen
Hiroshi Sato
Hitoshi Chiba
Hirotoshi Fuda
Chen Zhen
Hiroshi Sato
Application Number:
JP2018124331A
Publication Date:
January 10, 2023
Filing Date:
June 29, 2018
Export Citation:
Assignee:
National University Corporation Hokkaido University
Nissei Bio Co., Ltd.
Nissei Bio Co., Ltd.
International Classes:
A61K31/7048; A23L33/10; A23L33/105; A23L33/11; A61K31/352; A61K31/575; A61K36/8998; A61P39/06; A61P43/00
Domestic Patent References:
| JP2016196429A | ||||
| JP2016199501A |
Other References:
Nutrients,2017年,Vol.9, 1252,pp.1-14
J Basic Clin Physiol Pharmacol.,2016年,Vol.27, No.5,pp.473-482
日本未病システム学会雑誌,2015年,Vol.21, No.2,pp.167-170
日本食物繊維学会誌,2011年,Vol.15, No.2,p.119
J Basic Clin Physiol Pharmacol.,2016年,Vol.27, No.5,pp.473-482
日本未病システム学会雑誌,2015年,Vol.21, No.2,pp.167-170
日本食物繊維学会誌,2011年,Vol.15, No.2,p.119
Attorney, Agent or Firm:
Hiroki Masaki
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Matsunashi Yasunori
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Matsunashi Yasunori
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita
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