AGENT FOR INHIBITING MATRIX METALLOPROTEASE

Japanese Patent JP2003277259

A

To provide an agent for preventing and improving accentuation diseases of matrix metalloprotease which is characterized by containing at least one or more of fatty acids and/or salts of these fatty acids selected from the group consisting of palmitic acid, stearic acid, arachidinic acid, oleic acid, linolic acid, α-linolenic acid, γ-linolenic acid, arachidonic acid, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

The agent for preventing and improving accentuation diseases of matrix metalloprotease (MMP) is characterized by containing at least one or more of fatty acids and/or salts of these fatty acids selected from the group consisting of palmitic acid, stearic acid, arachidinic acid, oleic acid, linolic acid, α-linolenic acid, γ-linolenic acid, arachidonic acid, EPA and DHA. The above-mentioned fatty acids having inhibitory activity of MMP, and are useful for preventing and improving various diseases caused by accentuation of MMP, such as metastasis of cancer, ulceration, chronic arthrorheumatism, osteoporosis, paradentisis and the like.

JP2004527724	PYK2 (RAFTK) and inflammation
WO/2002/064595	TRIAZOLO COMPOUNDS AS MMP INHIBITORS
WO/2010/137696	ORAL MEDICINAL COMPOSITION AND ORAL MEDICINAL CAPSULE HAVING THE COMPOSITION ENCAPSULATED THEREIN

HATTORI KOJI
ITO MITSUAKI
MIZUTANI HIROSHI

JP2002083973A

October 02, 2003

March 25, 2002

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NONOGAWA SHOJI YK

A61P1/02; A61K31/20; A61K31/201; A61K31/202; A61P1/04; A61P19/02; A61P19/10; A61P29/00; A61P35/04; A61P43/00; (IPC1-7): A61K31/20; A61K31/201; A61K31/202; A61P1/02; A61P1/04; A61P19/02; A61P19/10; A61P29/00; A61P35/04; A61P43/00

JPH06166617A	1994-06-14
JPH0640904A	1994-02-15

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