To provide an alcohol dependence syndrome-treating medicine which can sequentially administer in a small amount of flumazenil to reduce the amount of the medicine per dose unit of administration target, can reduce alcohol withdrawal symptoms in a short time, can simultaneously administer a large amount of the medicine in a short time in single time to reduce side effects caused by the medicine, and can effectively administer the flumazenil.

This medicine prepared for treating alcohol dependence syndrome is characterized by being prepared so that the medicine can sequentially be administered in each flumazenil dose of 0.1 to 0.3 mg at a time interval of 1 to 15 min.