Title:
アルデヒド及びグリコシダーゼ処理した軟組織及び骨組織異種移植片
Document Type and Number:
Japanese Patent JP5015377
Kind Code:
B2
Abstract:
The invention provides a xenograft formed of a soft tissue for implantation into a human comprising a portion of the soft or bone tissue from a non-human animal, wherein the portion includes a plurality of extracellular components, a plurality of substantially only dead cells, and an aldehyde in an amount ranging from about 0.01 % to about 0.10 % crosslinking a plurality of proteins of the extracellular components, the extracellular components and the dead cells having substantially no surface carbohydrate moieties which are susceptible to glycosidase digestion, and whereby the portion is substantially non-immunogenic and has substantially the same mechanical properties as a corresponding portion of the native soft or bone tissue.
Inventors:
Kevin Earl Stone
Application Number:
JP2000598086A
Publication Date:
August 29, 2012
Filing Date:
February 08, 2000
Export Citation:
Assignee:
Aperion Biologics,Inc.
International Classes:
A61L27/00; A61F2/02; A61F2/08; A61F2/24; A61F2/28; A61F2/30; A61F2/38; A61L27/36
Domestic Patent References:
| JPS55122544A | 1980-09-20 |
Foreign References:
| US5782915A | 1998-07-21 | |||
| WO1998007837A1 | 1998-02-26 | |||
| WO1997012035A2 | 1997-04-03 |
Attorney, Agent or Firm:
Axis International Patent Business Corporation
Motohiro Kurauchi
Hiroshi Kazama
Motohiro Kurauchi
Hiroshi Kazama