Title:
細菌における多剤耐性の克服に使用されるアルギネートオリゴマー
Document Type and Number:
Japanese Patent JP5202764
Kind Code:
B2
Abstract:
The invention provides a method of overcoming resistance to at least one antibiotic in a multidrug resistant bacterium, said method comprising contacting said bacterium with an alginate oligomer together with the antibiotic. The multidrug resistant bacterium may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with a multidrug resistant bacterium to overcome resistance to the antibiotic in said multidrug resistant bacterium. In another aspect the method can be used to combat contamination of a site with multidrug resistant bacteria, e.g. for disinfection and cleaning purposes.
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Inventors:
Onsouen Edvar
MILVOLDE ROLF
Dessen Arne
Thomas david
Walsh Timothy Rutland
MILVOLDE ROLF
Dessen Arne
Thomas david
Walsh Timothy Rutland
Application Number:
JP2012513675A
Publication Date:
June 05, 2013
Filing Date:
June 03, 2010
Export Citation:
Assignee:
Argipharma Aes
International Classes:
A61K45/00; A01N43/16; A01N43/22; A01N61/00; A01N63/00; A01N63/02; A01P3/00; A61K8/73; A61K31/365; A61K31/7048; A61K31/7052; A61K47/36; A61P31/04
Domestic Patent References:
| JP2008540515A | ||||
| JP5252970A |
Other References:
北御門学ら,アルギン酸から酵素分解によって調製したオリゴ糖の静菌作用,日本水産学会誌,1993年,59(2),p.315-320
Hu Xiaokeら,Antibacterial activity of lyase-depolymerized products of alginate,Journal of Applied Phycology,2005年,17(1),p.57-60
Hu Xiaokeら,Antibacterial activity of lyase-depolymerized products of alginate,Journal of Applied Phycology,2005年,17(1),p.57-60
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office