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Title:
アルカリプロテアーゼ
Document Type and Number:
Japanese Patent JP5202690
Kind Code:
B2
Abstract:
The present invention provides an alkaline protease exhibiting high detergency and productivity, which is obtained by further enhancing the detergency of an alkaline protease effective against complex dirt and enhancing the specific activity. The alkaline protease of the present invention is obtained by applying one or more of the below-described modifications (a) through (e); i.e., amino acid residue substitution and/or insertion to an alkaline protease having the amino acid sequence of SEQ ID NO: 1 or an alkaline protease that is functionally equivalent thereto, and exhibits a specific activity and/or detergency higher than that of the alkaline protease having the amino acid sequence of SEQ ID NO: 1: (a) substitution, with an amino acid residue, of the amino acid residue at position 133 or at a position corresponding thereto; (b) insertion of an amino acid residue between the amino acid residues at positions 133 and 134 or at positions corresponding thereto; (c) substitution, with an amino acid residue, of the amino acid residue at original position 134 or at a position corresponding thereto; (d) substitution, with an amino acid residue, of the amino acid residue at original position 135 or at a position corresponding thereto; and (e) substitution, with an amino acid residue, of the amino acid residue at position 132 or at a position corresponding thereto.

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Inventors:
Mitsumi Okuda
Tsuyoshi Sato
Yasushi Takimura
Nobuyuki Sumitomo
Toru Kobayashi
Application Number:
JP2011123174A
Publication Date:
June 05, 2013
Filing Date:
June 01, 2011
Export Citation:
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Assignee:
Kao Corporation
International Classes:
C12N15/09; C11D3/386; C11D7/42; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/54
Domestic Patent References:
JP2002218989A
JP2002306176A
JP2003125783A
JP2004000122A
JP2004008085A
JP2004057195A
JP2004187669A
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto



 
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