To obtain a new alkyl 2-acetamido-2-deoxyglucopyranosidouronic acid and its derivative suitable for preventing and treating the aging of skin and useful as the cleansing surfactant or emulsifier of a cleaning agent for cosmetics.
An alkyl 2-acetamido-2-deoxy-D-glucopyranosidouronic acid of formula I or II (R is a 1-48C alkyl, a 1-48C acyl) and its pharmacologically or cosmetically permissible salt, e.g. stearyl 2-acetamido-2-deoxy-D- glucopyranosidouronic acid sodium salt. The compound of formula I or II is obtained by grinding chitin, treating the ground product with an acid and a primary aliphatic alcohol, if desired, dialyzing the obtained reaction product, reacting the purified reaction product with a secondary alcohol different from the primary aliphatic alcohol in the presence of an acid catalyst to liberate the primary aliphatic alcohol, if desired, distilling off the liberated primary aliphatic alcohol, and subsequently treating the reaction product with an acid.
JPS6169786 | SEPARATION PURIFICATION OF SUGAR ESTER |
JP2003055394 | NUCLEIC ACID-BINDING BICYCLOOCTANE DERIVATIVE |
HARTMUT SCHMIDT-LEVERKUEHNE
JOACHIM THIEM
SCHEEL OLIVER
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