Title:
ALKYLAMINO-AND ALKYLAMINO ALKYL DIARYLKETONE AND ITS PREPARATION
Document Type and Number:
Japanese Patent JPH04208255
Kind Code:
A
Abstract:
NEW MATERIAL: A compound of formula I [Ar is formula II (V is H, halogen, alkyl, alkoxy, CF3 or NO2; u is 1-3; X, Y are CF3 or CHF; Z, W are CH2, O, CHOH or CHF; m, n, p, q, and are 0 or 1; R1 is H or alkyl; and R2, R3 are alkyl)], their acid addition salts, and where applicable the geometric and optical isomers and racemic mixtures thereof.
EXAMPLE: 2-(3-Chlorophenyl)-1-[3-(dimethylamino)phenyl] ethanone.
USE: Pharmaceutical agents for alleviating various memory dysfunctins.
PROCESS: For example, a compound of formula I is obtained by reacting a compound of formula III (Hal stands for Cl, Br or I) with a compound of formula IV (R4 is carboxylic acid derivative).
Inventors:
RATSUSERU RICHIYAADO RII HAMAA
BURAIAN FURIIDO
RICHIYAADO CHIYAARUZU AREN
BURAIAN FURIIDO
RICHIYAADO CHIYAARUZU AREN
Application Number:
JP41919390A
Publication Date:
July 29, 1992
Filing Date:
December 13, 1990
Export Citation:
Assignee:
HOECHST ROUSSEL PHARMA
International Classes:
A61P25/00; A61P25/04; A61P25/28; C07C45/00; C07C45/45; C07C49/233; A61K31/135; C07C49/80; C07C217/48; C07C217/76; C07C217/86; C07C221/00; C07C225/16; C07C225/22; (IPC1-7): A61K31/135; C07C217/48; C07C217/76; C07C221/00; C07C225/16; C07C225/22
Attorney, Agent or Firm:
Chika Takagi (2 outside)