Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ALLYLALCOHOL COMPOUNDS AND THEIR PRODUCTION
Document Type and Number:
Japanese Patent JPH1017561
Kind Code:
A
Abstract:

To industrially advantageously obtain the subject new alcohol compound important as an intermediate for prostaglandins from easily available raw materials in advantageous productivity by stereospecifically reducing an α,β-unsaturated ketone.

The alcohol compound of formula I [R1 is methyl, ethyl, trifluoromethyl; R2 is methyl, ethyl, n-propyl; R3 is H, an OH-protecting group; (n) is 0, 1, 2]. The alcohol compound is preferably obtained by stereospecifically reducing (A) an α-unsaturated ketone of formula II with (B) a selective reducing agent, especially a reagent of formula III [R4 is a (substituted) 6-20C aryl; R5 is a (substituted) 2-6C alkyl]. The component A is preferably obtained by reacting (i) an aldehyde of formula IV with a phosphonate of formula V (R6 is a lower alkyl).


Inventors:
MATSUMURA YASUSHI
NAKANO TAKASHI
Application Number:
JP16485196A
Publication Date:
January 20, 1998
Filing Date:
June 25, 1996
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ASAHI GLASS CO LTD
International Classes:
C07D307/935; B01J31/14; C07B53/00; C07B61/00; C07C405/00; (IPC1-7): C07D307/935; B01J31/14; C07B53/00
Attorney, Agent or Firm:
Kenji Izumina