アマニチンコンジュゲート - Heidelberg Pharma Research Gezel Shaft Mitt Beschlenktel Haftung

Title:

アマニチンコンジュゲート

Document Type and Number:

Japanese Patent JP7362714

Kind Code:

B2

Abstract:

The invention relates to a conjugate comprising (a) an amatoxin comprising (i) an amino acid 4 with a 6'-deoxy position; and (ii) an amino acid 8 with an S-deoxy position; (b) a target-binding moiety; and (c) optionally a linker linking said amatoxin and said target-binding moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.

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Inventors:

Christian Lutz
Jan Andale
Christoph Muller
Berner Zimon
Zuzanne Berner-Simon
Tosten Hehiller
Michael Kurke

Application Number:

JP2021182011A

Publication Date:

October 17, 2023

Filing Date:

November 08, 2021

Export Citation:

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Assignee:

Heidelberg Pharma Research Gezel Shaft Mitt Beschlenktel Haftung

International Classes:

A61K47/65; A61K38/12; A61K39/395; A61K47/54; A61K47/68; A61P35/00; A61P35/02

Domestic Patent References:

JP2015519906A
JP2015533490A

Attorney, Agent or Firm:

Atsushi Aoki
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Hidenao Tsuda

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